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Adding blood pressure drug to standard antibiotics speeds up TB treatment

Infectious disease experts at Johns Hopkins have found, in studies in mice, that a drug better known as a treatment for high blood pressure and headaches effectively speeds up treatment of TB when...

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Learning how the brain takes out its trash may help decode neurological diseases

Imagine that garbage haulers don't exist. Slowly, the trash accumulates in our offices, our homes, it clogs the streets and damages our cars, causes illness and renders normal life impossible.

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Blood pressure drugs shown to decrease risk of Alzheimer's disease dementia

A Johns Hopkins-led analysis of data previously gathered on more than 3,000 elderly Americans strongly suggests that taking certain blood pressure medications to control blood pressure may reduce the...

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New guidelines for management of high blood pressure released

A new guideline for the management of high blood pressure, developed by an expert panel and containing nine recommendations and a treatment algorithm (flow chart) to help doctors treat patients with...

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Loose coupling between calcium channels and sensors

In research published in this week's online edition of Science, postdoc Nicholas Vyleta and Professor Peter Jonas of the Institute of Science and Technology Austria uncover the existence of loose...

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Sperm finding could improve fertility, contraceptives

(Medical Xpress)—A new study headed up by Cornell scientists has found that a component of the sperm membrane tightly controls a crucial step in fertilization, making it a prime target for efforts to...

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What you see is where you go: Fruit fly visual interneurons may compute...

(Medical Xpress)—The fruit fly Drosophila melanogaster is a model organism (a non-human species that is extensively studied to understand particular biological phenomena) studied in a wide range of...

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Role of calcium in familial Alzheimer's disease clarified, pointing to new...

In 2008 researchers at the Perelman School of Medicine at the University of Pennsylvania showed that mutations in two proteins associated with familial Alzheimer's disease (FAD) disrupt the flow of...

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Researchers identify regulation process of protein linked to bipolar disorder

Researchers from Tufts have gained new insight into a protein associated with bipolar disorder. The study, published in the June 3 issue of Science Signaling, reveals that calcium channels in resting...

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Researchers find link to failing heart in muscular dystrophy

(Medical Xpress)—In a world first, researchers at The University of Western Australia have discovered a communication breakdown may be responsible for causing heart failure in people with muscular...

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Gene variant linked to schizophrenia, bipolar disorder and alcoholism

A rare gene variant discovered by UCL (University College London) scientists is associated with an increased risk of developing schizophrenia, bipolar disorder and alcoholism, confirms new research.

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Researchers find an important clue to potential treatments for absence seizures

A group of Korean researchers has succeeded in revealing a principle mechanism of a neural network in the human brain, which will provide an important clue to potential treatments for absence seizures.

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Researchers unlock new mechanism in pain management

It's in the brain where we perceive the unpleasant sensations of pain, and researchers have long been examining how calcium channels in the brain and peripheral nervous system contribute to the...

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Muscular dystrophy: Repair the muscles, not the genetic defect

A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease.

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Scientists pioneer microscopy technique that yields fresh data on muscular...

Scientists at USC have developed a new microscopy technology that allows them to view single molecules in living animals at higher-than-ever resolution.

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Common blood pressure medication does not increase risk of breast cancer,...

Women who take a common type of medication to control their blood pressure are not at increased risk of developing breast cancer due to the drug, according to new study by researchers at the...

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The ryanodine receptor—calcium channel in muscle cells

Whenever muscles contract, so-called ryanodine receptors come into play. Calcium ions, which are ultimately responsible for the contraction of muscle cells, are released from storage organs and flow...

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Tackling neurotransmission precision

Behind all motor, sensory and memory functions, calcium ions are in the brain, making those functions possible. Yet neuroscientists do not entirely understand how fast calcium ions reach their targets...

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Study suggests worsening trends in headache management

Each year more than 12 million Americans visit their doctors complaining of headaches, which result in lost productivity and costs of upward of $31 billion annually. A new study by researchers from...

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Experts recommend weight loss drugs, surgery as supplement to lifestyle...

The Endocrine Society today issued a Clinical Practice Guideline (CPG) on strategies for prescribing drugs to manage obesity and promote weight loss.

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